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    YOUR GENES 101

    Overview

    Your genes play a key role in understanding and improving your overall health and well-being. Equally critical is how genetics shapes a deeper understanding of mental health treatment options, unleashing insights into better, more targeted and personal therapies that may help you

    The services Genomind® offers are designed to do just that. We put together this quick guide to genetics and genetics-related language. We hope this will help as you discuss the results of your Genomind Professional PGx ExpressTM test with your doctor.

    Lab test

    The Code to Your Genetic Makeup

    A cell is the basic unit of all living tissue. Within each cell is a nucleus, which contains your genetic information or genome. This genome is the sum of all genes, which are located on 23 pairs of chromosomes. Each chromosome contains a long strand of DNA. DNA is the code your body “reads” to create and recreate itself. Your genome, that is all of your DNA, contains about 20,000 genes.

    DNA is made up of four types of molecules called nucleotides, also known as bases, arranged in pairs. These base pairs make up the rungs of the DNA double helix. Your DNA contains some 3 billion pairs of nucleotides. Science has proven that 99.9% of DNA is identical in everyone. The remaining 0.1% contains the information that creates individuality. That 0.1% difference means millions of base pairs are different from person to person.

    As you learn about genetics, you will encounter the following key components:

    Trait

    A trait is a particular characteristic, quality or tendency you have. In science, a trait refers to something influenced by genetics.

     

    Gene

    Genes are sections of DNA and units of inherited information. Genes determine everything from the color of your eyes to your sensitivity to medication. Each gene has a specific location on a chromosome (known as a locus). There are two copies of each gene, one inherited from each parent, and the copies of each gene are not necessarily the same.

     

    Genotype

    A genotype is the particular combination of alleles, or variants, of a particular gene. An allele is one of a pair of genes at a particular location on a particular chromosome that serve the same function. When we say “your genotype” it means a pair of genes in your DNA that is responsible for a particular protein. The entire set of all of your genes, plus all the DNA between your genes, is called a genome.

     

    Prevalence

    The prevalence percentage shown next to each genotype is the percent of the population that has this genotype. NOTE: Prevalence in no way indicates a potential level of impact of that gene.

    Genomind Professional PGx Express is a test that looks at certain genes that may affect your body’s sensitivity or response to certain drugs and other treatments. Genomind Professional PGx Express is the leading test of its kind and looks at a group of key genes specific to mental health treatments. Your clinician can order this test for guidance that helps inform treatment decisions for you.

     

    About Genomind Professional PGx Express

    Genomind Professional PGx Express is a test that looks at certain genes that may affect your body’s sensitivity or response to certain drugs and other treatments. Genomind Professional PGx Express is the leading test of its kind and looks at a group of key genes specific to mental health treatments. Your clinician can order this test for guidance that helps inform treatment decisions for you.